NCCDPHP Work Group on Translation K2A Framework Glossary May 2010 1. Research phase: Discovery: The original biomedical, behavioral, or epidemiologic factor or finding that stimulated development of an intervention. Efficacy: The extent to which the intended effect or benefits were achieved under optimal conditions. Effectiveness: The extent to which the intended effect or benefits… Continue reading NCCDPHP Work Group on Translation and K2A Framework Glossary