How Do You Apply for an NPI? Health care providers may apply for an NPI in one of three ways: Option 1: Apply through a web-based application process. Visit theNational Plan and Provider Enumeration System (NPPES) at https://nppes.cms.hhs.gov/NPPES/Welcome.do on the CMS website. Individual providers must create a username and password through the Identity & Access… Continue reading How to apply for an NPI